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Healthy Hemp Resources You Can Count On

Have you heard of the Realm of Caring?If you’re a Healthy Hemp customer, or social media follower, you’ve probably heard us talk a lot about The Realm of Caring. Maybe we’ve even recommended the you give them a call!  It’s an amazing non-profit organization working to advance research, education, and advocacy around the science of cannabis. At Healthy Hemp, we love telling our customers to check out RoC resources. They work directly with the folks from Charlotte’s Web and they’re our go-to for tough questions.“We improve lives through Research, Education, and Advocacy. By funding and conducting Research, we learn more about cannabis and its effects while legitimizing the therapy. Education empowers consumers to select the best products for their individual needs, and informs healthcare professionals about options for their patients. Through Advocacy, we spread the truth about cannabis and expand access to those in need.Here’s how RoC can help YOU!Dosing recommendations Talk to a specialist Explore their research Check out their FAQs here

Healthy Hemp helps you to be Informed!

This means that some companies are more concerned with cashing-in than providing top quality products that truly help customers. It’s really important that you do your homework on hemp. We did a lot of research before starting Healthy Hemp! We only wanted to work with companies creating products in the best interest of their customers – it’s why we’ve partnered withCharlotte’s Web Hemp Extract and PlusCBDOil.
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  • Message Board: Join our forum and hear from other users about their experiences.
Healthy Hemp’s done the homework for you this week. The peeps behind PlusCBDOil are taking time to really examine how CBD oil can influence your endocannabinoid system and what that means for anxiety and depression. In this article, The Endocannabinoid System and CBD’s Role in Stress, Anxiety, and Fear Responses, the authors talk about several studies and how CBD is reducing the fight or flight response and other fear-based responses in both mice and humans in clinical trials. Need more info? Read this article from Herb. Learn about the role the human Endocannabinoid System plays in our nervous systems. And, hear how former UFC pro Bas Rutten is using CBD for physical and emotional pain. Sticking with this brand “I was surprised to notice that it lessened my pain and helped a little with anxiety. It wasn’t a super miracle that wiped out all pain and ailments but it certainly did make it manageable. I noticed the pain in my knees lessened to where I didn’t want to scream after bending down. I do think I could use a higher dose and so ill be trying the 500mg next. I did try another brand of CBD oil and it certainly didn’t compare as far as taste as well as benefits and seemed too chemically. Blah! I’ll stick with this brand!”   -Deanna Finally relief from stabbing pain! “The 35 mg. CBD capsules that I bought from you have helped greatly with my osteoarthritis! It has also lessened the pain from fibromyalgia on really bad days, and has eliminated it on regular days. I can’t thank you enough! I will definitely be a regular customer! Plus, I have to say your staff and service are friendly, knowledgeable, informative, and the delivery is very fast. Thank you just doesn’t seem to say enough. But, THANK YOU!!”  -Jane Even the Skeptic loves it! “I’ve noticed a huge change in my anxiety and lack of sleep. I’m finally sleeping through the night and it’s wonderful. I’ve also been able to manage my pain from a fall down wet stairs followed by a car accident two weeks later without any pain medications. Even my husband, who was a bit skeptical and hasn’t used the oil over the last few weeks, plans to start using it again after not sleeping so well again and his anxiety has kicked up again. Hint for using the mint flavored…. Follow it with some chocolate milk! We use the dark chocolate almond milk. So good!”  -Angela

Sharing your story helps other families find answers and relief and builds community.

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Healthy Hemp: We want be the positive change!

Forbes reported that the CBD market will grow to a $2.1 billion market in consumer sales by 2020 with $450 million of those sales coming from hemp-based sources. That’s a 700% increase from 2016. The industry is growing fast! And, Healthy Hemp is keeping up with the changes and working to bring you the latest innovations, products, and information.

Share your Healthy Hemp Story Sharing your story helps other families find answers and relief and builds community.

Share your stories on our forum and social media!

The Endocannabinoid System and CBD’s Role in Stress, Anxiety, and Fear Responses

*Article originally published by www.leafly.com and shared by Healthy Hemp, as an informational customer resource.This article is sponsored by PlusCBD Oil, a product line from CV Sciences (formerly CannaVest). CV Sciences is one of the leading suppliers and manufacturers of agricultural hemp-derived CBD bulk and finished products.
The biological mechanisms that control mood, anxiety, stress, fear, and other emotional behavior have been focused almost exclusively on the role of certain neurotransmitters called monoamines. While monoamines like dopamine, serotonin, and norepinephrine play an important role in controlling mood and anxiety, the vast majority of drug-based therapies that target those “monoaminergic” systems are limited in their efficacy.More recently, research has begun to highlight other neurochemical systems, including cytokines, peptides, and bioactive lipids. By diving deeper into the science of bioactive lipids, we begin to unearth the potential role of the endocannabinoid system (ECS) in stress and fear responses.

The Endocannabinoid System’s Role in the Human Body

The ECS has been described as a complex physiologic network within the human body comprised of cannabinoid receptors (CB1 and CB2). There are endogenous cannabinoid compounds such as anandamide and 2-AG, and their respective enzymes responsible for maintaining balance in the system by regulating the synthesis and breakdown of the active endocannabinoid compounds.Not surprisingly, cannabinoid receptors and the biochemical machinery necessary to synthesize and generate cannabinoids are present within areas of the brain known to control emotional behavior, mood, stress, and fear. These structures include the prefrontal cortex, amygdala, hippocampus, and periaqueductal gray (PAG) of the midbrain.

What Happens in the Brain When Cannabinoid Receptors are Activated?

Preclinical studies in mice have clearly shown that activation of cannabinoid receptors within the PAG via direct injection of anandamide reduces panic and anxiety behavior, or the “fight or flight” phenomenon. Other studies using a similar model in animals have shown decreased fear-avoidant and conditioned responses to pain or punishment.However, before we jump the gun and feel like we have fear, anxiety, and stress responses all figured out, it’s not as simple as activating receptors through cannabinoid administration. Other animal studies utilizing systemic injections of Δ9-THC (not directly into the PAG of the midbrain) have demonstrated mixed responses, eliciting either anxiogenic (promoting increased levels of anxiety) or anxiolytic (decreasing levels of anxiety).This bidirectional or paradoxical response appears to be dose-dependent, where lower doses seem to reduce stress, anxiety, and panic, while higher doses may promote increased feelings of stress, panic, and fear. These opposing effects are likely a result of the involvement of other neurotransmitter circuits within the brain that, when inhibited, actually create a hyper-excitable response of stress, anxiety, and fear.

Striking a Balance Within the Cannabinoid System

To illustrate what neuroscientists currently feel is happening, think of being in a car with the brake pedal and accelerator. When the cannabinoid system is functioning to decrease fear, stress, and panic, the foot is being taken off of the accelerator in the areas of PAG-midbrain centers.On the other hand, when dosing is too high, or there is an imbalance in the endocannabinoid system, whereby CB1 receptors are being over-activated in lieu of CB2, that’s like taking the foot off the brake pedal, thereby removing inhibition that was normally in place and allowing the engine to rev higher—increased fear, anxiety, and stress from activation of other circuits in the brain that are normally applying the brake.More recently, other preclinical research has demonstrated the important role of maintaining a healthy endocannabinoid system “tone” for improved stress resilience and reducing the residual post-traumatic anxiety, fear, and panic behaviors in mice that were chronically exposed to stress. Interestingly, the greater the exposure to stress, the greater the magnitude of the response to treatment (by improving the ECS and cannabinoid signaling).

Are Cannabinoid Compounds the “Gatekeepers” to Healthy Stress Levels?

One theory is that anadamide and 2-AG are acting as “gatekeepers” to keep the stress response and high emotional loads at bay and improving recovery to pre-stress levels once the stress burden is reduced to baseline. Moreover, there is evidence from preliminary human studies that disrupting endocannabinoid signaling and regulation has important impacts on the HPA (hypothalamic-pituitary-adrenal) axis by increasing signs of anxiety and depression.There is an emerging role in the interplay between the immune system and the neuro-endocrine system, such that the field of psychoneuroimmunology has exploded with new basic and preclinical research over the past 5 years. The crosstalk between the immune system, cytokine signaling, and the nervous system influencing behavior, anxiety, and mood has been proposed by numerous preclinical studies. A number of recent studies have demonstrated a role of CB2 receptors classically associated with the immune system in anxiety and depression-related behavior in animal models and human clinical studies.In this context, it’s interesting to note that a balanced ECS appears to be pivotal to a healthy stress response and mitigating fear, anxiety, and panic that tend to accumulate with dysfunctional responses to stress.

CBD and Anxiety Reduction in Humans

A randomized, double-blind, placebo controlled trial in 15 humans demonstrated that up to 600 mg of CBD (cannabidiol) reduced measured anxiety compared to increased levels with a 10 mg dose of Δ9-THC. CBD appears to activate other receptors outside CB2, including 5HT1A and TRPV1, both of which are involved in the anxiolytic and mitigating panic/fear responses to stress.The totality of the best available scientific evidence points to the importance of balancing the tone of the endocannabinoid system for supporting a healthy stress response. This preclinical and emerging human clinical data support the use of a CBD-rich or CBD-overweighted extract of cannabis for modulating fear, anxiety, and a healthy stress response. 

CBD and Hemp article References:

Campos AC, Ferreira FR, Guimarães FS. Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: possible involvement of 5HT1A receptors. J Psychiatr Res. 2012 Nov;46(11):1501-10.Campos AC, Guimarães FS. Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Nov 13;33(8):1517-21.Fusar-Poli P, Crippa JA, Bhattacharyya S, et al. Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing. Arch Gen Psychiatry. 2009 Jan;66(1):95-105.Hill MN, Patel S. Translational evidence for the involvement of the endocannabinoid system in stress-related psychiatric illnesses. Biol Mood Anxiety Disord. 2013 Oct 22;3(1):19.Saito VM, Wotjak CT, Moreira FA. Pharmacological exploitation of the endocannabinoid system: new perspectives for the treatment of depression and anxiety disorders. Rev Bras Psiquiatr. 2010 May;32 Suppl 1:S7-14.Witkin JM, Tzavara ET, Nomikos GG. A role for cannabinoid CB1 receptors in mood and anxiety disorders. Behav Pharmacol. 2005 Sep;16(5-6):315-31.

Your Guide to Taking CW Hemp Products

*Healthy Hemp sharing this blog post originally published by CWHemp.com
 We’ve received remarkable feedback from so many CW customers who report positive results from using Charlotte’s Web products. If you’re just getting started or moving up to a different strength, you might not be getting your desired results yet because you haven’t found the perfect amount of CW for your individual needs. That can be frustrating. No one wants to feel like Goldilocks, bouncing between “too much” and “too little.” We want to help you find the amount that’s juuuust right – your CW sweet spot. 


Healthy Hemp Morning Boost Recipes


Morning Boost Smoothie 
1 medium banana 6 strawberries 1 date Hand full of blueberries 1/2 cup ice 1 cup almond milk Handful kale or spinach (kids won’t notice the spinach at all!) Spoonful of peanut butter or PB powder 1mg CW Everyday Plus Chocolate Mint Whirl it all in a blender and enjoy. For kids-be sure to get a thick straw or put it in one of your to-go coffee mugs to drink on the way to school. Morning Boost Coffee:  Got to get kids organized an out the door in the morning? Try a dropper of CW Hemp Chocolate Mint in your morning coffee for flavor and, maybe an extra dash of focus.

Healthy Hemp Helping Families: Kristen and Jackson

Healthy Hemp and Autism The latest estimate of autism prevalence—1 in 68—is up 30 percent from the 1 in 88 rate reported in 2008, and more than double the 1 in 150 rate in 2000. In fact, the trend has been steeply upward since the early 1990s, not only in the U.S. but globally. *www.scientificamerican.com Could all-natural Hemp Extracts supplements be something these families could really benefit from? You be the judge. We receive many reviews from customers that have family members with autism disorders and they all have the highest of hopes! In fact, we would love to introduce you to our very own Kristen Lux and her son, Jackson! Kristen has been a part of the Healthy Hemp team for a little over 5 months now, and she quickly witnessed how the hemp extract products were giving her son a better quality of life! Jackson’s mom, Kristen, is happy to report that her son is finding relief thanks to Healthy Hemp. But, it wasn’t always that way. When he was 3, Jackson was diagnosed with Autism Spectrum Disorder (ASD). His family saw other kids developing and hitting the usual milestones while Jackson was non-verbal. Before trying hemp extracts, his family struggled to coach 5 words out of him a day. He was anxious and had regular meltdowns; including self-harming behaviors and screaming from sensory overload. Kristen began researching ways to help Jackson cope. “The more research I did, the more I kept running into information on the benefits of hemp extracts. The Charlotte’s Web brand in particular.” She says Healthy Hemp was full of useful information and pointed her to resources like The Realm of Caring where she got proper dosing information. Now, Jackson is thriving! Kristen says, “His growth in the past 5 months has been so dramatic it is incredible. Jackson’s doctors and therapists are all amazed with the benefits of Charlotte’s Web and how well it is working for us!” Kristen encourages other families to research hemp extracts and understand how it they might benefit you, or someone you know. She says, “Don’t be afraid to asking all the questions that are running through your head about it! Better understanding was the first huge step for me.” Healthy Hemp is thrilled to see this little guy doing so well!

Good Gut Health = Better Mental Health

Thank goodness mental health issues are no longer a taboo topic!

*originally published by CWHemp.com

At this point, if you haven’t personally had the joy of even mild anxiety or depression, you likely have a friend or loved one who’s experienced some mood issues. In fact, nearly seventeen percent of Americans are filling prescriptions for psychiatric drugs to treat these diagnoses, among others (1). Clearly, we have mental health on the mind.

One of the most interesting, reassuring and exciting developments in mental health is that potty talk has also lost its stigma with the discovery that our gut influences how we feel, and it’s not to be confused with gut stress after eating a spicy curry. Scientists now call our gastrointestinal tract our “2nd brain” (2) because while high-level reasoning and detailed thought processes are still handled by the brain brain, many of our ideas and feelings are dictated by the 30 feet organ running from the end of our esophagus to the anus.

This lengthy tract is where a network of 100 million neurons (2) carries information from the gut to our brain’s gray matter. Meaning, our enteric nervous system and gut microbiome (both science-y names for our GI tract) inform what goes on in our head. This has led scientists to reason that the source of anxiety and depression – in some cases—could be the war-torn lining of a gut that’s battled (among other things) over-the-counter and prescription drugs, everyday toxins in our environment, or low-quality, antagonistic foods (and not just the occasional spicy Indian dish).

Finding good solutions for matters of the mind has been tricky, with many turning to the long-term use of SSRIs (selective serotonin reuptake inhibitors). These pills can come with side effects that may not be desirable, chief of which is the recent discovery that their medical formulations disrupt the lining of the gut. And if the gut is disrupted, so is our brain.  So yes, you read that correctly – the drugs many take for anxiety and depression could create symptoms of anxiety and depression.

Thankfully researchers have found many alternative and complementary ways to calm our mind – easy, daily changes for soothing the gut and a few other key areas of the body.

Foods

The Journal of Neuroscience noted, “changes to the gut microbiome can affect emotional behavior and related brain systems.”(3) Thankfully this works both ways – meaning that you can double down and add beneficial foods to bolster healthy bacteria in your gut, while also eliminating foods that cause the 2nd brain incite internal warfare. (And you do NOT want to get caught on that firing line.)

 Remove the bad – Gluten, dairy, soy, refined sugar, and alcohol may cause “neuropsychiatric disorders including major depression” according to a study in Biological Psychiatry (4). Decreasing intake of these foods can reduce the angst in your digestive system and mind. But don’t just take our word for it. Try a 30-day elimination diet to see what reactions, if any, these foods cause within your body.

Add the good – After removing the unfriendly foods, add some nourishing ones, supportive of a happy enteric nervous system, such as:

Prebiotic foods (foods that feed beneficial bacteria) – onions, bananas, onions, raw garlic, and fresh dandelion greens, to name a few.

Probiotic supplements or probiotic-dense foods – this includes sauerkraut, pickles, kefir and other fermented foods.

 Other positive ways to influence your mental health:

Supplements

Cannabidiol (CBD) – We bet you can guess our favorite way to boost gut health…cannabinoids! Non-psychoactive and non-addictive, cannabinoids have shown positive effects for anxiety and depressive behaviors. (5) And, Charlotte’s Web is better than CBD alone. It contains a full spectrum of beneficial cannabinoids and plant compounds missing in single isolate CBD versions. (Many believe that these compounds work together to heighten their positive effect. Scientists call this the Entourage Effect.) Our Charlotte’s Web Everyday Hemp is a specially formulated blend of cannabinoids, naturally occurring antioxidants, and neuroprotectants.

Omega 3s- The positive effects of eating fish twice a week or supplementing for similar levels with a high-quality fish oil high in omega-3s has scientists intrigued as they’ve seen repeated studies showing polyunsaturated fatty acids as a valuable addition to depression treatments, and a possible aid in lowering future risk of depression. (6) (7)

Vitamin D – This vitamin plays a massive role in our mood. “Increasingly vitamin D deficiency is being associated with a number of psychiatric conditions,” according to an Australian research study (8). Since “Vitamin D is a member of the superfamily of nuclear steroid transcription regulators…[it] exerts control over a large number of genes.”(9) And it’s these genes that “regulate the immune system and release neurotransmitters that affect brain function and development.”(10) All of which is science talk to say- Vitamin D is a big player in the normal processes of our body, including mental health.

Physical Activity

Want to hear something awesome? Research studies show aerobic exercise being as effective in reducing depression as prescription medications.(11) This could be from supervised classes at the gym or at-home online sessions. …Suddenly Zumba class sounds a lot more appealing.

Whichever options you choose, we salute you and support you in caring for your — not one, but — two dynamic brains.

Have you experienced a correlation between your gut health and your mental health? Has taking CW seemed to improve digestion or food allergies? Tell us more!

References:

1. One in 6 Americans Take Antidepressants, Other Psychiatric Drugs: Study

http://www.nbcnews.com/health/health-news/one-6-americans-take-antidepressants-other-psychiatric-drugs-n695141

citing:

Adult Utilization of Psychiatric Drugs and Differences by Sex, Age, and Race

http://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2592697

2. Think Twice: How the Gut’s “Second Brain” Influences Mood and Well-Being

https://www.scientificamerican.com/article/gut-second-brain/

3. Gut Microbes and the Brain: Paradigm Shift in Neuroscience

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228144/

4. Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression.

https://www.ncbi.nlm.nih.gov/pubmed/19150053

5. Cannabidiol, neuroprotection and neuropsychiatric disorders

https://www.researchgate.net/publication/292679412_Cannabidiol_neuroprotection_and_neuropsychiatric_disorders

6. Mayo Clinic.org: Depression

http://www.mayoclinic.org/diseases-conditions/depression/expert-answers/fish-oil-supplements/faq-20058143

7. Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid?

https://www.ncbi.nlm.nih.gov/pubmed/17877810

8. Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease.

https://www.ncbi.nlm.nih.gov/pubmed/22796576

9. Vitamin D and the brain.

https://www.ncbi.nlm.nih.gov/pubmed/21872806

10. Psychology Today

https://www.psychologytoday.com/blog/the-breakthrough-depression-solution/201111/psychological-consequences-vitamin-d-deficiency

11. Exercise and pharmacotherapy in the treatment of major depressive disorder. https://www.ncbi.nlm.nih.gov/pubmed/17846259

What is CBD Oil?

Unlike medical marijuana products, which are usually made from plants with high concentrations of psychoactive tetrahydrocannabinol (THC), CBD hemp oil is made from high-CBD, low-THC hemp. Because hemp contains only trace amounts of THC, these CBD oil products are non-psychoactive.
What is CBD Oil?